Ontology highlight
ABSTRACT:
SUBMITTER: Seppala H
PROVIDER: S-EPMC105397 | biostudies-literature | 1998 Feb
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 19980201 2
Erythromycin resistance among streptococci is commonly due to target site modification by an rRNA-methylating enzyme, which results in coresistance to macrolide, lincosamide, and streptogramin B antibiotics (MLSB resistance). Genes belonging to the ermAM (ermB) gene class are the only erythromycin resistance methylase (erm) genes in Streptococcus pyogenes with MLSB resistance that have been sequenced so far. We identified a novel erm gene, designated ermTR, from an erythromycin-resistant clinica ...[more]