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ABSTRACT: Aims
Recent studies suggest that atrial fibrillation (AF) burden (time AF is present) is an independent risk factor for stroke. The aim of this trial was to study the feasibility and accuracy to identify AF episodes and quantify AF burden in patients with a known history of paroxysmal AF with a photoplethysmography (PPG)-based wearable.Methods and results
In this prospective, single-centre trial, the PPG-based estimation of AF burden was compared with measurements of a conventional 48 h Holter electrocardiogram (ECG), which served as the gold standard. An automated algorithm performed PPG analysis, while a cardiologist, blinded for the PPG data, analysed the ECG data. Detected episodes of AF measured by both methods were aligned timewise.Out of 100 patients recruited, 8 had to be excluded due to technical issues. Data from 92 patients were analysed [55.4% male; age 73.3 years (standard deviation, SD: 10.4)]. Twenty-five patients presented AF during the study period. The intraclass correlation coefficient of total AF burden minutes detected by the two measurement methods was 0.88. The percentage of correctly identified AF burden over all patients was 85.1% and the respective parameter for non-AF time was 99.9%.Conclusion
Our results demonstrate that a PPG-based wearable in combination with an analytical algorithm appears to be suitable for a semiquantitative estimation of AF burden in patients with a known history of paroxysmal AF.Trial registration number
NCT04563572.
SUBMITTER: Reissenberger P
PROVIDER: S-EPMC10545505 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Reissenberger Pamela P Serfözö Peter P Piper Diana D Juchler Norman N Glanzmann Sara S Gram Jasmin J Hensler Karina K Tonidandel Hannah H Börlin Elena E D'Souza Marcus M Badertscher Patrick P Eckstein Jens J
European heart journal. Digital health 20230706 5
<h4>Aims</h4>Recent studies suggest that atrial fibrillation (AF) burden (time AF is present) is an independent risk factor for stroke. The aim of this trial was to study the feasibility and accuracy to identify AF episodes and quantify AF burden in patients with a known history of paroxysmal AF with a photoplethysmography (PPG)-based wearable.<h4>Methods and results</h4>In this prospective, single-centre trial, the PPG-based estimation of AF burden was compared with measurements of a convention ...[more]