Ontology highlight
ABSTRACT:
SUBMITTER: Barrio-Alonso E
PROVIDER: S-EPMC10564971 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Barrio-Alonso Estibaliz E Lituma Pablo J PJ Notaras Michael J MJ Albero Robert R Bouchekioua Youcef Y Wayland Natalie N Stankovic Isidora N IN Jain Tanya T Gao Sijia S Calderon Diany Paola DP Castillo Pablo E PE Colak Dilek D
Cell reports 20230411 4
The regulation of neurons by circadian clock genes is thought to contribute to the maintenance of neuronal functions that ultimately underlie animal behavior. However, the impact of specific circadian genes on cellular and molecular mechanisms controlling synaptic plasticity and cognitive function remains elusive. Here, we show that the expression of the circadian protein TIMELESS displays circadian rhythmicity in the mammalian hippocampus. We identify TIMELESS as a chromatin-bound protein that ...[more]