Micro-syringe chip-guided intratumoral administration of lipid nanoparticles for targeted anticancer therapy.
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ABSTRACT:
SUBMITTER: Kim J
PROVIDER: S-EPMC10577945 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Publications
Micro-syringe chip-guided intratumoral administration of lipid nanoparticles for targeted anticancer therapy.
Kim Jeongrae J Song Sunejeong S Gwak Minjun M Cho Hanhee H Yun Wan Su WS Hwang Namcheol N Kim Jinseong J Lee Jun Seo JS Kim Dong-Hwee DH Kim Hyuncheol H Jeon Seong Ik SI Kim Tae-Il TI Kim Kwangmeyung K
Biomaterials research 20231016 1
<h4>Background</h4>Nano-sized drug delivery system has been widely studied as a potential technique to promote tumor-specific delivery of anticancer drugs due to its passive targeting property, but resulting in very restricted improvements in its systemic administration so far. There is a requirement for a different approach that dramatically increases the targeting efficiency of therapeutic agents at targeted tumor tissues.<h4>Methods</h4>To improve the tumor-specific accumulation of anticancer ...[more]
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