Ontology highlight
ABSTRACT:
SUBMITTER: Adrian PV
PROVIDER: S-EPMC105785 | biostudies-literature | 1998 Sep
REPOSITORIES: biostudies-literature
Adrian P V PV DU Plessis M M Klugman K P KP Amyes S G SG
Antimicrobial agents and chemotherapy 19980901 9
The nucleotide sequence of a plasmid-borne trimethoprim resistance gene from a commensal fecal Escherichia coli isolate revealed a new dihydrofolate reductase gene, dfrXV, which occurred as a gene cassette integrated in a site-specific manner in a class 1 integron. The new gene shows 84% nucleotide identity and the predicted protein shows 90% amino acid identity with dfrI and DHFR type I, respectively. Genes for spectinomycin resistance, aadA1 [ant (3")-Ia], and sulfonamide resistance, sulI, wer ...[more]