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Two new dfr genes in trimethoprim-resistant integron-negative Escherichia coli isolates.

ABSTRACT: Two Escherichia coli isolates resistant to trimethoprim but negative for integrons carried two new resistance genes, dfrA24 and dfrA26, remotely similar to one another and to the cassette-independent genes dfrA8 and dfrA9. The dfrA24 gene was not associated with known mobile elements, while dfrA26 was associated with the CR1 common region.

SUBMITTER: Grape M 

PROVIDER: S-EPMC1855533 | biostudies-literature | 2007 May

REPOSITORIES: biostudies-literature

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Two new dfr genes in trimethoprim-resistant integron-negative Escherichia coli isolates.

Grape M M   Sundström L L   Kronvall G G  

Antimicrobial agents and chemotherapy 20070216 5

Two Escherichia coli isolates resistant to trimethoprim but negative for integrons carried two new resistance genes, dfrA24 and dfrA26, remotely similar to one another and to the cassette-independent genes dfrA8 and dfrA9. The dfrA24 gene was not associated with known mobile elements, while dfrA26 was associated with the CR1 common region. ...[more]

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