Ontology highlight
ABSTRACT:
SUBMITTER: Behrends J
PROVIDER: S-EPMC1061632 | biostudies-literature | 2005 Apr
REPOSITORIES: biostudies-literature
Behrends Jens J Clément Serge S Pajak Bernard B Pohl Viviane V Maenhaut Carine C Dumont Jacques E JE Schurmans Stéphane S
Molecular and cellular biology 20050401 7
Rhophilin 2 is a Rho GTPase binding protein initially isolated by differential screening of a chronically thyrotropin (TSH)-stimulated dog thyroid cDNA library. In thyroid cell culture, expression of rhophilin 2 mRNA and protein is enhanced following TSH stimulation of the cyclic AMP (cAMP) transduction cascade. Yeast two-hybrid screening and coimmunoprecipitation have revealed that the GTP-bound form of RhoB and components of the cytoskeleton are protein partners of rhophilin 2. These results l ...[more]