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Presence of tetracycline resistance determinants and susceptibility to tigecycline and minocycline.


ABSTRACT: No relation between the presence of tetracycline resistance determinants tet(A) to tet(E) and the MICs of tigecycline was observed for Enterobacteriaceae, although tetracycline-susceptible isolates were more susceptible overall to tigecycline, whereas the presence of tet(M) in Staphylococcus aureus was associated with higher MICs of minocycline.

SUBMITTER: Fluit AC 

PROVIDER: S-EPMC1068614 | biostudies-literature | 2005 Apr

REPOSITORIES: biostudies-literature

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Presence of tetracycline resistance determinants and susceptibility to tigecycline and minocycline.

Fluit Ad C AC   Florijn Alice A   Verhoef Jan J   Milatovic Dana D  

Antimicrobial agents and chemotherapy 20050401 4


No relation between the presence of tetracycline resistance determinants tet(A) to tet(E) and the MICs of tigecycline was observed for Enterobacteriaceae, although tetracycline-susceptible isolates were more susceptible overall to tigecycline, whereas the presence of tet(M) in Staphylococcus aureus was associated with higher MICs of minocycline. ...[more]

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