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Next-generation MRI scanner designed for ultra-high-resolution human brain imaging at 7 Tesla.


ABSTRACT: To increase granularity in human neuroimaging science, we designed and built a next-generation 7 Tesla magnetic resonance imaging scanner to reach ultra-high resolution by implementing several advances in hardware. To improve spatial encoding and increase the image signal-to-noise ratio, we developed a head-only asymmetric gradient coil (200 mT m-1, 900 T m-1s-1) with an additional third layer of windings. We integrated a 128-channel receiver system with 64- and 96-channel receiver coil arrays to boost signal in the cerebral cortex while reducing g-factor noise to enable higher accelerations. A 16-channel transmit system reduced power deposition and improved image uniformity. The scanner routinely performs functional imaging studies at 0.35-0.45 mm isotropic spatial resolution to reveal cortical layer functional activity, achieves high angular resolution in diffusion imaging and reduces acquisition time for both functional and structural imaging.

SUBMITTER: Feinberg DA 

PROVIDER: S-EPMC10703687 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature

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To increase granularity in human neuroimaging science, we designed and built a next-generation 7 Tesla magnetic resonance imaging scanner to reach ultra-high resolution by implementing several advances in hardware. To improve spatial encoding and increase the image signal-to-noise ratio, we developed a head-only asymmetric gradient coil (200 mT m<sup>-1</sup>, 900 T m<sup>-1</sup>s<sup>-1</sup>) with an additional third layer of windings. We integrated a 128-channel receiver system with 64- and  ...[more]

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