Ontology highlight
ABSTRACT:
SUBMITTER: Gray-Edwards HL
PROVIDER: S-EPMC4060963 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Gray-Edwards Heather L HL Salibi Nouha N Josephson Eleanor M EM Hudson Judith A JA Cox Nancy R NR Randle Ashley N AN McCurdy Victoria J VJ Bradbury Allison M AM Wilson Diane U DU Beyers Ronald J RJ Denney Thomas S TS Martin Douglas R DR
Journal of neuroscience methods 20140210
<h4>Background</h4>Feline models of neurologic diseases, such as lysosomal storage diseases, leukodystrophies, Parkinson's disease, stroke and NeuroAIDS, accurately recreate many aspects of human disease allowing for comparative study of neuropathology and the testing of novel therapeutics. Here we describe in vivo visualization of fine structures within the feline brain that were previously only visible post mortem.<h4>New method</h4>3Tesla MR images were acquired using T1-weighted (T1w) 3D mag ...[more]