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[Tandem mass tag-based quantitative proteomics analysis of plasma and plasma exosomes in Parkinson's disease].


ABSTRACT:

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC10719805 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature

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[Tandem mass tag-based quantitative proteomics analysis of plasma and plasma exosomes in Parkinson's disease].

Zhao Yuan Y   Liu Xin X   Zhang Yidan Y   Zhang Jian J   Liu Xiang X   Yang Guofeng G  

Se pu = Chinese journal of chromatography 20231201 12


The cardinal clinical features of Parkinson's disease (PD), a common neurodegenerative disease, include the irreversible impairment of movement coordination, such as tremors, gait rigidity, bradykinesia, and hypokinesia. Although various factors are associated with the pathological changes in PD, such as oxidative stress, mitochondrial dysfunction, and neuroinflammation, the availability of treatments to retard PD progression is limited. Therefore, novel biomarkers for PD diagnosis and therapeut  ...[more]

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