A genome-wide association study of social trust in 33,882 Danish blood donors.
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ABSTRACT:
SUBMITTER: Sequeros CB
PROVIDER: S-EPMC10792163 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
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A genome-wide association study of social trust in 33,882 Danish blood donors.
Sequeros Celia Burgos CB Hansen Thomas Folkmann TF Westergaard David D Louloudis Ioannis I Kalamajski Sebastian S Röder Timo T Rohde Palle Duun PD Schwinn Michael M Clemmensen Line Harder LH Didriksen Maria M Nyegaard Mette M Hjalgrim Henrik H Nielsen Kaspar René KR Bruun Mie Topholm MT Ostrowski Sisse Rye SR Erikstrup Christian C Mikkelsen Susan S Sørensen Erik E Pedersen Ole Birger Vestager OBV Brunak Søren S Banasik Karina K Giordano Giuseppe Nicola GN
Scientific reports 20240116 1
Social trust is a heritable trait that has been linked with physical health and longevity. In this study, we performed genome-wide association studies of self-reported social trust in n = 33,882 Danish blood donors. We observed genome-wide and local evidence of genetic similarity with other brain-related phenotypes and estimated the single nucleotide polymorphism-based heritability of trust to be 6% (95% confidence interval = (2.1, 9.9)). In our discovery cohort (n = 25,819), we identified one s ...[more]
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