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Integrating porphyrin-based nanoporous organic polymers with electrochemical aptasensors for ultratrace detection of kanamycin.

ABSTRACT: The synthesis and characterization of two new porphyrin-based porous organic polymers (POPs) via Sonogashira cross-coupling reaction and leverage the two obtained POPs is reported for the fabrication of electrochemical aptasensors to detect kanamycin at an ultratrace level. The resultant electrochemical aptasensor demonstrates a high linear relationship with the logarithmic value of kanamycin concentration in the range 5 × 10^-5-5 μg/L with the limit of detection of 17.6 pg/L or 36.3 fM. During the analysis of real samples from milk and river, a relative standard deviation of less than 4.39%, and good recovery values in the range 97.0-105% were obtained.

SUBMITTER: Tian G

PROVIDER: S-EPMC10794321 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature

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Integrating porphyrin-based nanoporous organic polymers with electrochemical aptasensors for ultratrace detection of kanamycin.

Tian Guanghui G Guo Feng F Fan Chuanbin C Zong Zi-Ao ZA Wang Junli J Tegudeer Zhuorigebatu Z Gao Wen-Yang WY

Mikrochimica acta 20240117 2

The synthesis and characterization of two new porphyrin-based porous organic polymers (POPs) via Sonogashira cross-coupling reaction and leverage the two obtained POPs is reported for the fabrication of electrochemical aptasensors to detect kanamycin at an ultratrace level. The resultant electrochemical aptasensor demonstrates a high linear relationship with the logarithmic value of kanamycin concentration in the range 5 × 10<sup>-5</sup>-5 μg/L with the limit of detection of 17.6 pg/L or 36.3 f ...[more]

PMID: 38231429

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