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Residual Immunity from Smallpox Vaccination and Possible Protection from Mpox, China.

ABSTRACT: Among persons born in China before 1980 and tested for vaccinia virus Tiantan strain (VVT), 28.7% (137/478) had neutralizing antibodies, 71.4% (25/35) had memory B-cell responses, and 65.7% (23/35) had memory T-cell responses to VVT. Because of cross-immunity between the viruses, these findings can help guide mpox vaccination strategies in China.

SUBMITTER: Huang Y

PROVIDER: S-EPMC10826747 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature

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Residual Immunity from Smallpox Vaccination and Possible Protection from Mpox, China.

Huang Yu Y Guo Li L Li Yanan Y Ren Lili L Nie Jiqin J Xu Fengwen F Huang Tingxuan T Zhong Jingchuan J Fan Zhangling Z Zhang Yin Y Xie Yu Y Zhang Qiao Q Mei Shan S Xiao Yan Y Wang Xinming X Xu Liuhui L Guo Fei F Wang Jianwei J

Emerging infectious diseases 20240201 2

Among persons born in China before 1980 and tested for vaccinia virus Tiantan strain (VVT), 28.7% (137/478) had neutralizing antibodies, 71.4% (25/35) had memory B-cell responses, and 65.7% (23/35) had memory T-cell responses to VVT. Because of cross-immunity between the viruses, these findings can help guide mpox vaccination strategies in China. ...[more]

PMID: 38270156

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