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ABSTRACT: Purpose
To compare laser flare photometry (LFP) measurements of aqueous flare with Standardization of Uveitis Nomenclature (SUN) and modified SUN grading.Methods
In this prospective study with multicenter design, uveitis patients were classified according to SUN and modified SUN grading scales. LFP was performed with Kowa FM-700 flaremeter. Mean LFP values were compared with SUN and MSUN scores.Results
The study included 475 LFP measurements, of which 216, 48, 150, 31, 28 and 2 had 0, 0.5+, 1+, 1.5+, 2+ and 3+ flare, respectively. LFP values were significantly different between each two consecutive steps for both clinical gradings (all P < .05). Cut-off values for modified SUN grading steps were defined as 5.7, 9.7, 15.7 and 43.2 for 0/0.5+, 0.5+/ 1+, 1+/1.5+ and 1.5/2+ borders of clinical flare, respectively.Conclusions
LFP proves to be an objective measurement in analyzing aqueous flare comparable to both SUN and MSUN clinical grading systems.
SUBMITTER: Halim MS
PROVIDER: S-EPMC10863987 | biostudies-literature | 2022 Oct-Nov
REPOSITORIES: biostudies-literature
Halim Muhammad Sohail MS Hasanreisoglu Murat M Onghanseng Neil N Tran Anh N T ANT Hassan Muhammad M Yilmaz Mervenur M Segawa Asadu A Gurelik Gokhan G Afridi Rubbia R Ormaechea Maria Soledad MS Uludag Gunay G Kesim Cem C Nguyen Nam V NV Bae Jeong Hun JH Park Jung Huynh JH Do Diana V DV Ibrahim Mohamed A MA Sepah Yasir J YJ Nguyen Quan Dong QD
Ocular immunology and inflammation 20220126 7-8
<h4>Purpose</h4>To compare laser flare photometry (LFP) measurements of aqueous flare with Standardization of Uveitis Nomenclature (SUN) and modified SUN grading.<h4>Methods</h4>In this prospective study with multicenter design, uveitis patients were classified according to SUN and modified SUN grading scales. LFP was performed with Kowa FM-700 flaremeter. Mean LFP values were compared with SUN and MSUN scores.<h4>Results</h4>The study included 475 LFP measurements, of which 216, 48, 150, 31, 28 ...[more]