Surface analyses and immune reactivities of major cell wall-associated proteins of group a streptococcus.
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ABSTRACT:
SUBMITTER: Cole JN
PROVIDER: S-EPMC1087385 | biostudies-literature | 2005 May
REPOSITORIES: biostudies-literature
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Surface analyses and immune reactivities of major cell wall-associated proteins of group a streptococcus.
Cole Jason N JN Ramirez Ruben D RD Currie Bart J BJ Cordwell Stuart J SJ Djordjevic Steven P SP Walker Mark J MJ
Infection and immunity 20050501 5
A proteomic analysis was undertaken to identify cell wall-associated proteins of Streptococcus pyogenes. Seventy-four distinct cell wall-associated proteins were identified, 66 of which were novel. Thirty-three proteins were immunoreactive with pooled S. pyogenes-reactive human antisera. Biotinylation of the GAS cell surface identified 23 cell wall-associated proteins that are surface exposed. ...[more]
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