N-Glycan Profiles of Neuraminidase from Avian Influenza Viruses.
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ABSTRACT:
SUBMITTER: Chen W
PROVIDER: S-EPMC10893399 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
Publications
<i>N</i>-Glycan Profiles of Neuraminidase from Avian Influenza Viruses.
Chen Wentian W Ma Tianran T Liu Sinuo S Zhong Yaogang Y Yu Hanjie H Shu Jian J Wang Xiurong X Li Zheng Z
Viruses 20240126 2
The cleavage of sialic acids by neuraminidase (NA) facilitates the spread of influenza A virus (IV) descendants. Understanding the enzymatic activity of NA aids research into the transmission of IVs. An effective method for purifying NA was developed using <i>p</i>-aminophenyloxamic acid-modified functionalized hydroxylated magnetic particles (AAMPs), and from 0.299 to 0.401 mg of NA from eight IV strains was isolated by 1 mg AAMP. A combination of lectin microarrays and MALDI-TOF/TOF-MS was emp ...[more]
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