Ontology highlight
ABSTRACT:
SUBMITTER: Galhardo RS
PROVIDER: S-EPMC1092274 | biostudies-literature | 2005
REPOSITORIES: biostudies-literature
Galhardo Rodrigo S RS Rocha Raquel P RP Marques Marilis V MV Menck Carlos F M CF
Nucleic acids research 20050510 8
DNA polymerases of the Y-family, such as Escherichia coli UmuC and DinB, are specialized enzymes induced by the SOS response, which bypass lesions allowing the continuation of DNA replication. umuDC orthologs are absent in Caulobacter crescentus and other bacteria, raising the question about the existence of SOS mutagenesis in these organisms. Here, we report that the C.crescentus dinB ortholog is not involved in damage-induced mutagenesis. However, an operon composed of two hypothetical genes a ...[more]