Ontology highlight
ABSTRACT:
SUBMITTER: Ji K
PROVIDER: S-EPMC10922861 | biostudies-literature | 2024 Feb
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20240206 7
Nidulaxanthone A is a dimeric, dihydroxanthone natural product that was isolated in 2020 from <i>Aspergillus sp</i>. Structurally, the compound features an unprecedented heptacyclic 6/6/6/6/6/6/6 ring system which is unusual for natural xanthone dimers. Biosynthetically, nidulaxanthone A originates from the monomer nidulalin A via stereoselective Diels-Alder dimerization. To expedite the synthesis of nidulalin A and study the proposed dimerization, we developed methodology involving the use of a ...[more]