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Use of Maribavir for Multidrug Resistant Cytomegaloviremia in a Pediatric Oncology Patient.


ABSTRACT: Resistant and refractory cytomegalovirus (CMV) viremia can limit the provision of chemotherapy due to myelosuppression and end-organ dysfunction. Few therapies are available for children with clinically significant CMV viremia. We successfully used maribavir for a 4-year-old patient with lymphoma to complete his chemotherapy course. Resistance to maribavir did result after many months of therapy.

SUBMITTER: Fisher JE 

PROVIDER: S-EPMC10956659 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature

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Use of Maribavir for Multidrug Resistant Cytomegaloviremia in a Pediatric Oncology Patient.

Fisher James E JE   Mulieri Kevin K   Finch Elizabeth E   Ericson Jessica E JE  

Journal of pediatric hematology/oncology 20240301 3


Resistant and refractory cytomegalovirus (CMV) viremia can limit the provision of chemotherapy due to myelosuppression and end-organ dysfunction. Few therapies are available for children with clinically significant CMV viremia. We successfully used maribavir for a 4-year-old patient with lymphoma to complete his chemotherapy course. Resistance to maribavir did result after many months of therapy. ...[more]

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