Ontology highlight
ABSTRACT:
SUBMITTER: Akiyoshi DE
PROVIDER: S-EPMC109691 | biostudies-literature | 1998 May
REPOSITORIES: biostudies-literature
Akiyoshi D E DE Denaro M M Zhu H H Greenstein J L JL Banerjee P P Fishman J A JA
Journal of virology 19980501 5
Endogenous retroviruses of swine are a concern in the use of pig-derived tissues for xenotransplantation into humans. The nucleotide sequence of porcine endogenous retrovirus taken from lymphocytes of miniature swine (PERV-MSL) has been characterized. PERV-MSL is a type C retrovirus of 8,132 bp with the greatest nucleic acid sequence identity to gibbon ape leukemia virus and murine leukemia virus. Constitutive production of PERV-MSL RNA has been detected in normal leukocytes and in multiple orga ...[more]