Porcine endogenous retrovirus transmission characteristics of an inbred herd of miniature swine.
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ABSTRACT:
SUBMITTER: Oldmixon BA
PROVIDER: S-EPMC135987 | biostudies-literature | 2002 Mar
REPOSITORIES: biostudies-literature
Publications
Porcine endogenous retrovirus transmission characteristics of an inbred herd of miniature swine.
Oldmixon Beth A BA Wood James C JC Ericsson Thomas A TA Wilson Carolyn A CA White-Scharf Mary E ME Andersson Goran G Greenstein Julia L JL Schuurman Henk-Jan HJ Patience Clive C
Journal of virology 20020301 6
Here we report the identification of inbred miniature swine that failed to produce human-tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro coculture assays. When HTRC PERVs were isolated from transmitting animals, all were recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-related sequences. ...[more]
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