Ontology highlight
ABSTRACT:
SUBMITTER: Wang Q
PROVIDER: S-EPMC10970339 | biostudies-literature | 2024 Mar
REPOSITORIES: biostudies-literature
Wang Qinghua Q Zhao Jing J Liu Zhaoyuan Z Ding Shaoxiong S Huang Zhiyong Z Chen Jun J
International journal of molecular sciences 20240308 6
The marine bacterium <i>Streptomyces</i> sp. HNS054 shows promise as a platform for producing natural products. Isolated from a marine sponge, HNS054 possesses several desirable traits for bioengineering: rapid growth, salt tolerance, and compatibility with genetic tools. Its genome contains 21 potential biosynthetic gene clusters, offering a rich source of natural products. We successfully engineered HNS054 to increase the production of aborycin and actinorhodin by 4.5-fold and 1.2-fold, respec ...[more]