Ontology highlight
ABSTRACT:
SUBMITTER: Li S
PROVIDER: S-EPMC11009309 | biostudies-literature | 2024 Apr
REPOSITORIES: biostudies-literature
Li Shuang S Yang Hongtao H Qu Xinhua X Qin Yu Y Liu Aobo A Bao Guo G Huang He H Sun Chaoyang C Dai Jiabao J Tan Junlong J Shi Jiahui J Guan Yan Y Pan Wei W Gu Xuenan X Jia Bo B Wen Peng P Wang Xiaogang X Zheng Yufeng Y
Nature communications 20240411 1
Reconciling the dilemma between rapid degradation and overdose toxicity is challenging in biodegradable materials when shifting from bulk to porous materials. Here, we achieve significant bone ingrowth into Zn-based porous scaffolds with 90% porosity via osteoinmunomodulation. At microscale, an alloy incorporating 0.8 wt% Li is employed to create a eutectoid lamellar structure featuring the LiZn<sub>4</sub> and Zn phases. This microstructure optimally balances high strength with immunomodulation ...[more]