Cortico-cerebellar coordination facilitates neuroprosthetic control.
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ABSTRACT:
SUBMITTER: Abbasi A
PROVIDER: S-EPMC11014440 | biostudies-literature | 2024 Apr
REPOSITORIES: biostudies-literature
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Cortico-cerebellar coordination facilitates neuroprosthetic control.
Abbasi Aamir A Rangwani Rohit R Bowen Daniel W DW Fealy Andrew W AW Danielsen Nathan P NP Gulati Tanuj T
Science advances 20240412 15
Temporally coordinated neural activity is central to nervous system function and purposeful behavior. Still, there is a paucity of evidence demonstrating how this coordinated activity within cortical and subcortical regions governs behavior. We investigated this between the primary motor (M1) and contralateral cerebellar cortex as rats learned a neuroprosthetic/brain-machine interface (BMI) task. In neuroprosthetic task, actuator movements are causally linked to M1 "direct" neurons that drive th ...[more]
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