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Multiple alleles of Treponema pallidum repeat gene D in Treponema pallidum isolates.


ABSTRACT: Two new tprD alleles have been identified in Treponema pallidum: tprD2 is found in 7 of 12 T. pallidum subsp. pallidum isolates and 7 of 8 non-pallidum isolates, and tprD3 is found in one T. pallidum subsp. pertenue isolate. Antibodies against TprD2 are found in persons with syphilis, demonstrating that tprD2 is expressed during infection.

SUBMITTER: Centurion-Lara A 

PROVIDER: S-EPMC111288 | biostudies-literature | 2000 Apr

REPOSITORIES: biostudies-literature

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Multiple alleles of Treponema pallidum repeat gene D in Treponema pallidum isolates.

Centurion-Lara A A   Sun E S ES   Barrett L K LK   Castro C C   Lukehart S A SA   Van Voorhis W C WC  

Journal of bacteriology 20000401 8


Two new tprD alleles have been identified in Treponema pallidum: tprD2 is found in 7 of 12 T. pallidum subsp. pallidum isolates and 7 of 8 non-pallidum isolates, and tprD3 is found in one T. pallidum subsp. pertenue isolate. Antibodies against TprD2 are found in persons with syphilis, demonstrating that tprD2 is expressed during infection. ...[more]

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