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Properties of various Rho1 mutant alleles of Cryptococcus neoformans.


ABSTRACT: The RHO1 homologue of Cryptococcus neoformans complemented Saccharomyces cerevisiae rho1 mutations. The results of overexpression and site-specific mutagenesis of CnRHO1 in C. neoformans and S. cerevisiae indicated that although CnRHO1 could functionally substitute for the RHO1 gene of S. cerevisiae, mutants of cnrho1 manifested unique features in certain aspects.

SUBMITTER: Chang YC 

PROVIDER: S-EPMC111380 | biostudies-literature | 2000 Sep

REPOSITORIES: biostudies-literature

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Properties of various Rho1 mutant alleles of Cryptococcus neoformans.

Chang Y C YC   Penoyer L A LA  

Journal of bacteriology 20000901 17


The RHO1 homologue of Cryptococcus neoformans complemented Saccharomyces cerevisiae rho1 mutations. The results of overexpression and site-specific mutagenesis of CnRHO1 in C. neoformans and S. cerevisiae indicated that although CnRHO1 could functionally substitute for the RHO1 gene of S. cerevisiae, mutants of cnrho1 manifested unique features in certain aspects. ...[more]

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