Ontology highlight
ABSTRACT:
SUBMITTER: Yoshioka N
PROVIDER: S-EPMC111623 | biostudies-literature | 2000 Jan
REPOSITORIES: biostudies-literature
Yoshioka N N Inoue H H Nakanishi K K Oka K K Yutsudo M M Yamashita A A Hakura A A Nojima H H
Journal of virology 20000101 2
We have reported that suppressive factors for transformation by viral oncogenes are expressed in primary rat embryo fibroblasts (REFs). To identify such transformation suppressor genes, we prepared a subtracted cDNA library by using REFs and a rat normal fibroblast cell line, F2408, and isolated 30 different cDNA clones whose mRNA expression was markedly reduced in F2408 cells relative to that in REFs. We referred to these as TRIF (transcript reduced in F2408) clones. Among these genes, we initi ...[more]