Unknown

Dataset Information

0

Simultaneous electrochemical determination of uric acid and hypoxanthine at a TiO2/graphene quantum dot-modified electrode.


ABSTRACT: A TiO2/graphene quantum dots composite (TiO2/GQDs) obtained by in situ synthesis of GQDs, derived from coffee grounds, and peroxo titanium complexes was used as electrode modifier in the simultaneous electrochemical determination of uric acid and hypoxanthine. The TiO2/GQDs material was characterized by photoluminescence, X-ray diffraction, Raman spectroscopy, high-resolution transmission electron microscopy, and energy-dispersive X-ray mapping. The TiO2/GQDs-GCE exhibits better electrochemical activity for uric acid and hypoxanthine than GQDs/GCE or TiO2/GCE in differential pulse voltammetry (DPV) measurements. Under optimized conditions, the calibration plots were linear in the range from 1.00 to 15.26 μM for both uric acid and hypoxanthine. The limits of detection of this method were 0.58 and 0.68 μM for uric acid and hypoxanthine, respectively. The proposed DPV method was employed to determine uric acid and hypoxanthine in urine samples with acceptable recovery rates.

SUBMITTER: Ngoc Hoang V 

PROVIDER: S-EPMC11196949 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature

altmetric image

Publications

Simultaneous electrochemical determination of uric acid and hypoxanthine at a TiO<sub>2</sub>/graphene quantum dot-modified electrode.

Ngoc Hoang Vu V   Hoa Dang Thi Ngoc DTN   Quang Man Nguyen N   Son Le Vu Truong LVT   Son Le Van Thanh LVT   Nguyen Vo Thang VT   Phong Le Thi Hong LTH   Diem Ly Hoang LH   Ly Kieu Chan KC   Thang Ho Sy HS   Quang Khieu Dinh D  

Beilstein journal of nanotechnology 20240620


A TiO<sub>2</sub>/graphene quantum dots composite (TiO<sub>2</sub>/GQDs) obtained by in situ synthesis of GQDs, derived from coffee grounds, and peroxo titanium complexes was used as electrode modifier in the simultaneous electrochemical determination of uric acid and hypoxanthine. The TiO<sub>2</sub>/GQDs material was characterized by photoluminescence, X-ray diffraction, Raman spectroscopy, high-resolution transmission electron microscopy, and energy-dispersive X-ray mapping. The TiO<sub>2</su  ...[more]

Similar Datasets

| S-EPMC10933321 | biostudies-literature
| S-EPMC9922001 | biostudies-literature
| S-EPMC9626542 | biostudies-literature
| S-EPMC9054048 | biostudies-literature
| S-EPMC8576758 | biostudies-literature
| S-EPMC6641499 | biostudies-literature
| S-EPMC7866594 | biostudies-literature
| S-EPMC6648597 | biostudies-literature
| S-EPMC9070778 | biostudies-literature
| S-EPMC9557743 | biostudies-literature