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Palliative care and COVID-19: acknowledging past mistakes to forge a better future.


ABSTRACT:

Context

COVID-19 induces complex distress across physical, psychological, and social realms and palliative care (PC) has the potential to mitigate this suffering significantly.

Objectives

To describe the clinical characteristics and outcomes of COVID-19 patients with an indication of PC, compared to patients who had no indication, in different pandemic waves.

Methods

This retrospective multicenter observational cohort included patients from 40 hospitals, admitted from March 2020 to August 2022. Patients who had an indication of palliative care (PC) described in their medical records were included in the palliative care group (PCG), while those who had no such indication in their medical records were allocated to the non-palliative care group (NPCG).

Results

Out of 21,158 patients, only 6.7% had indication for PC registered in their medical records. The PCG was older, had a higher frequency of comorbidities, exhibited higher frailty, and had a higher prevalence of clinical complications and mortality (81.4% vs. 17.7%, p < 0.001), when compared to the NPCG. Regarding artificial life support, the PCG had a higher frequency of dialysis (20.4% vs. 10.1%, p < 0.001), invasive mechanical ventilation (48.2% vs. 26.0%, p < 0.001) and admission to the intensive care unit (53.6% vs. 35.4%, p < 0.001). These differences were consistent across all three waves.

Conclusion

A low proportion of patients received PC. Patients in PCG were more fragile, had more clinical complications, and had a higher mortality. On the contrary to our expectations, they received more artificial life support in all three waves. Taken together, these findings suggest that decisions regarding PC indication were made too late, within a context of end-of-life and therapeutic failure.

SUBMITTER: de Andrade CRM 

PROVIDER: S-EPMC11306131 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature

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Publications

Palliative care and COVID-19: acknowledging past mistakes to forge a better future.

de Andrade Camila Rabelo Monteiro CRM   Luz Fernanda Silva Trindade FST   de Oliveira Neimy Ramos NR   Kopittke Luciane L   Santa Rosa Luiza Marinho Motta LMM   Gomes Angelica Gomides Dos Reis AGDR   Bartolazzi Frederico F   Francisco Saionara Cristina SC   da Costa Felicio Roberto FR   Jorge Alzira de Oliveira AO   Cimini Christiane Corrêa Rodrigues CCR   Carneiro Marcelo M   Ruschel Karen Brasil KB   Schwarzbold Alexandre Vargas AV   Ponce Daniela D   Ferreira Maria Angélica Pires MAP   Guimarães Júnior Milton Henriques MH   Silveira Daniel Vitório DV   Aranha Fernando Graça FG   de Carvalho Rafael Lima Rodrigues RLR   de Godoy Mariana Frizzo MF   Viana Lucas Macedo Pereira LMP   Hirakata Vânia Naomi VN   Bicalho Maria Aparecida Camargos MAC   Marcolino Milena Soriano MS  

Frontiers in medicine 20240725


<h4>Context</h4>COVID-19 induces complex distress across physical, psychological, and social realms and palliative care (PC) has the potential to mitigate this suffering significantly.<h4>Objectives</h4>To describe the clinical characteristics and outcomes of COVID-19 patients with an indication of PC, compared to patients who had no indication, in different pandemic waves.<h4>Methods</h4>This retrospective multicenter observational cohort included patients from 40 hospitals, admitted from March  ...[more]

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