Dataset Information

Clinical Outcomes After Drug-Coated Balloon Treatment in Popliteal Artery Disease: K-POP Registry 12-Month Results.

ABSTRACT:

Background and objectives

The popliteal artery is generally regarded as a "no-stent zone." Limited data are available on the outcomes of drug-coated balloons (DCBs) for popliteal artery disease. This study aimed to evaluate the 12-month clinical outcomes among patients who received DCB treatment for atherosclerotic popliteal artery disease.

Methods

This prospective, multicenter registry study enrolled 100 patients from 7 Korean endovascular centers who underwent endovascular therapy using IN.PACT DCB (Medtronic) for symptomatic atherosclerotic popliteal artery disease. The primary endpoint was 12-month clinical primary patency and the secondary endpoint was clinically driven target lesion revascularization (TLR)-free rate.

Results

The mean age of the study cohort was 65.7±10.8 years, and 77% of enrolled patients were men. The mean lesion length was 93.7±53.7 mm, and total occlusions were present in 45% of patients. Technical success was achieved in all patients. Combined atherectomy was performed in 17% and provisional stenting was required in 11%. Out of the enrolled patients, 91 patients completed the 12-month follow-up. Clinical primary patency and TLR-free survival rates at 12 months were 76.0% and 87.2%, respectively. A multivariate Cox regression analysis identified female and longer lesion length as the significant independent predictors of loss of patency.

Conclusions

DCB treatment yielded favorable 12-month clinical primary patency and TLR-free survival outcomes in patients with popliteal artery disease.

Trial registration

ClinicalTrials.gov Identifier: NCT02698345.

SUBMITTER: Park JI

PROVIDER: S-EPMC11306430 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature

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Publications

Clinical Outcomes After Drug-Coated Balloon Treatment in Popliteal Artery Disease: K-POP Registry 12-Month Results.

Park Jong-Il JI Ko Young-Guk YG Lee Seung-Jun SJ Ahn Chul-Min CM Rha Seung-Woon SW Yu Cheol-Woong CW Park Jong Kwan JK Park Sang-Ho SH Lee Jae-Hwan JH Kim Su-Hong SH Lee Yong-Joon YJ Hong Sung-Jin SJ Kim Jung-Sun JS Kim Byeong-Keuk BK Hong Myeong-Ki MK Choi Donghoon D

Korean circulation journal 20240429 8

<h4>Background and objectives</h4>The popliteal artery is generally regarded as a "no-stent zone." Limited data are available on the outcomes of drug-coated balloons (DCBs) for popliteal artery disease. This study aimed to evaluate the 12-month clinical outcomes among patients who received DCB treatment for atherosclerotic popliteal artery disease.<h4>Methods</h4>This prospective, multicenter registry study enrolled 100 patients from 7 Korean endovascular centers who underwent endovascular thera ...[more]

PMID: 38767445

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Dataset Information

Clinical Outcomes After Drug-Coated Balloon Treatment in Popliteal Artery Disease: K-POP Registry 12-Month Results.

Background and objectives

Methods

Results

Conclusions

Trial registration

Publications

Clinical Outcomes After Drug-Coated Balloon Treatment in Popliteal Artery Disease: K-POP Registry 12-Month Results.

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