Ontology highlight
ABSTRACT:
SUBMITTER: Takefman DM
PROVIDER: S-EPMC114208 | biostudies-literature | 2001 May
REPOSITORIES: biostudies-literature
Journal of virology 20010501 10
The pig genome contains porcine endogenous retroviruses (PERVs) capable of infecting human cells. Detection of infectious retrovirus in porcine peripheral blood mononuclear cells and endothelial cells suggested to us that pig plasma is likely to contain PERV. Both PERV env sequences and viral reverse transcriptase (RT) activity were detected in all plasma samples isolated from four NIH minipigs. To detect infectious virus from plasma, we performed a culture assay using three cell lines of feline ...[more]