Ontology highlight
ABSTRACT:
SUBMITTER: Parker JS
PROVIDER: S-EPMC114880 | biostudies-literature | 2001 Apr
REPOSITORIES: biostudies-literature
Parker J S JS Murphy W J WJ Wang D D O'Brien S J SJ Parrish C R CR
Journal of virology 20010401 8
Canine parvovirus (CPV) enters and infects cells by a dynamin-dependent, clathrin-mediated endocytic pathway, and viral capsids colocalize with transferrin in perinuclear vesicles of cells shortly after entry (J. S. L. Parker and C. R. Parrish, J. Virol. 74:1919-1930, 2000). Here we report that CPV and feline panleukopenia virus (FPV), a closely related parvovirus, bind to the human and feline transferrin receptors (TfRs) and use these receptors to enter and infect cells. Capsids did not detecta ...[more]