The vanB2 gene cluster of the majority of vancomycin-resistant Enterococcus faecium isolates from Taiwan is associated with the pbp5 gene and is carried by Tn5382 containing a novel insertion sequence.
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ABSTRACT:
SUBMITTER: Lu JJ
PROVIDER: S-EPMC1195393 | biostudies-literature | 2005 Sep
REPOSITORIES: biostudies-literature
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The vanB2 gene cluster of the majority of vancomycin-resistant Enterococcus faecium isolates from Taiwan is associated with the pbp5 gene and is carried by Tn5382 containing a novel insertion sequence.
Lu Jang-Jih JJ Chang Tein-Yao TY Perng Cherng-Lih CL Lee Shih-Yi SY
Antimicrobial agents and chemotherapy 20050901 9
Thirty-two vanB2 Enterococcus faecium isolates were found to harbor Tn5382. Twenty-four isolates had a 1,419-bp sequence inserted within the open reading frame (ORF) C of Tn5382. This 1,419-bp sequence contained a 638-bp ORF with a 72% amino acid sequence homology with the transposase gene of IS150. Thirty isolates had the pbp5 gene linked to Tn5382. ...[more]
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