Ontology highlight
ABSTRACT:
SUBMITTER: Miretti MM
PROVIDER: S-EPMC1199300 | biostudies-literature | 2005 Apr
REPOSITORIES: biostudies-literature
Miretti Marcos M MM Walsh Emily C EC Ke Xiayi X Delgado Marcos M Griffiths Mark M Hunt Sarah S Morrison Jonathan J Whittaker Pamela P Lander Eric S ES Cardon Lon R LR Bentley David R DR Rioux John D JD Beck Stephan S Deloukas Panos P
American journal of human genetics 20050301 4
Autoimmune, inflammatory, and infectious diseases present a major burden to human health and are frequently associated with loci in the human major histocompatibility complex (MHC). Here, we report a high-resolution (1.9 kb) linkage-disequilibrium (LD) map of a 4.46-Mb fragment containing the MHC in U.S. pedigrees with northern and western European ancestry collected by the Centre d'Etude du Polymorphisme Humain (CEPH) and the first generation of haplotype tag single-nucleotide polymorphisms (ta ...[more]