Ontology highlight
ABSTRACT:
SUBMITTER: Koyama T
PROVIDER: S-EPMC1200254 | biostudies-literature | 2005 Sep
REPOSITORIES: biostudies-literature
Koyama Tetsuo T McHaffie John G JG Laurienti Paul J PJ Coghill Robert C RC
Proceedings of the National Academy of Sciences of the United States of America 20050906 36
Our subjective sensory experiences are thought to be heavily shaped by interactions between expectations and incoming sensory information. However, the neural mechanisms supporting these interactions remain poorly understood. By using combined psychophysical and functional MRI techniques, brain activation related to the intensity of expected pain and experienced pain was characterized. As the magnitude of expected pain increased, activation increased in the thalamus, insula, prefrontal cortex, a ...[more]