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PCR detection of human cytomegalovirus DNA in clinical specimens using novel UL37 exon 3 and US3 primers.


ABSTRACT: The sensitivity and specificity of novel UL37 exon 3 (UL37x3) and US3 immediate-early (IE) gene PCR primers to detect human cytomegalovirus (HCMV) DNA in clinical specimens are comparable to those of HCMV DNA polymerase (UL54) primers. The use of these IE primers increases the diagnostic performance of HCMV PCR.

SUBMITTER: Lesperance MM 

PROVIDER: S-EPMC121369 | biostudies-literature | 1998 Mar

REPOSITORIES: biostudies-literature

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PCR detection of human cytomegalovirus DNA in clinical specimens using novel UL37 exon 3 and US3 primers.

Lesperance M M MM   Contopoulos-Ioannidis D G DG   del Pilar Gutiérrez M M   Colberg-Poley A M AM  

Clinical and diagnostic laboratory immunology 19980301 2


The sensitivity and specificity of novel UL37 exon 3 (UL37x3) and US3 immediate-early (IE) gene PCR primers to detect human cytomegalovirus (HCMV) DNA in clinical specimens are comparable to those of HCMV DNA polymerase (UL54) primers. The use of these IE primers increases the diagnostic performance of HCMV PCR. ...[more]

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