Ontology highlight
ABSTRACT:
SUBMITTER: Desai KV
PROVIDER: S-EPMC124512 | biostudies-literature | 2002 May
REPOSITORIES: biostudies-literature
Desai Kartiki V KV Xiao Nianqing N Wang Weili W Gangi Lisa L Greene John J Powell John I JI Dickson Robert R Furth Priscilla P Hunter Kent K Kucherlapati Raju R Simon Richard R Liu Edison T ET Green Jeffrey E JE
Proceedings of the National Academy of Sciences of the United States of America 20020501 10
Molecular expression profiling of tumors initiated by transgenic overexpression of c-myc, c-neu, c-ha-ras, polyoma middle T antigen (PyMT) or simian virus 40 T/t antigen (T-ag) targeted to the mouse mammary gland have identified both common and oncogene-specific events associated with tumor formation and progression. The tumors shared great similarities in their gene-expression profiles as compared with the normal mammary gland with an induction of cell-cycle regulators, metabolic regulators, zi ...[more]