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AbeM, an H+-coupled Acinetobacter baumannii multidrug efflux pump belonging to the MATE family of transporters.

ABSTRACT: We cloned a gene, abeM, for a multidrug efflux pump from Acinetobacter baumannii using Escherichia coli as the host. Sequence analysis revealed that AbeM is a member of the MATE family of pumps. AbeM was found to be an H(+)-coupled multidrug efflux pump and a unique member of the MATE family.

SUBMITTER: Su XZ 

PROVIDER: S-EPMC1251516 | biostudies-literature | 2005 Oct

REPOSITORIES: biostudies-literature

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AbeM, an H+-coupled Acinetobacter baumannii multidrug efflux pump belonging to the MATE family of transporters.

Su Xian-Zhong XZ   Chen Jing J   Mizushima Tohru T   Kuroda Teruo T   Tsuchiya Tomofusa T  

Antimicrobial agents and chemotherapy 20051001 10

We cloned a gene, abeM, for a multidrug efflux pump from Acinetobacter baumannii using Escherichia coli as the host. Sequence analysis revealed that AbeM is a member of the MATE family of pumps. AbeM was found to be an H(+)-coupled multidrug efflux pump and a unique member of the MATE family. ...[more]

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