Ontology highlight
ABSTRACT:
SUBMITTER: Wardleworth BN
PROVIDER: S-EPMC125410 | biostudies-literature | 2002 Sep
REPOSITORIES: biostudies-literature
Wardleworth B N BN Russell R J M RJ Bell S D SD Taylor G L GL White M F MF
The EMBO journal 20020901 17
Eukaryotic DNA is packaged into nucleosomes that regulate the accessibility of the genome to replication, transcription and repair factors. Chromatin accessibility is controlled by histone modifications including acetylation and methylation. Archaea possess eukary otic-like machineries for DNA replication, transcription and information processing. The conserved archaeal DNA binding protein Alba (formerly Sso10b) interacts with the silencing protein Sir2, which regulates Alba's DNA binding affini ...[more]