Ontology highlight
ABSTRACT:
SUBMITTER: Guo HS
PROVIDER: S-EPMC125836 | biostudies-literature | 2002 Feb
REPOSITORIES: biostudies-literature
Guo Hui Shan HS Ding Shou Wei SW
The EMBO journal 20020201 3
Post-transcriptional gene silencing (PTGS) provides protection against viruses in plants by homology-dependent RNA degradation. PTGS initiated locally produces a mobile signal that instructs specific RNA degradation at a distance. Here we show that this signal-mediated intercellular spread of PTGS does not occur after PTGS initiation in cells expressing cucumber mosaic virus 2b protein (Cmv2b), a nucleus-localized plant viral PTGS suppressor. Silencing spread via the signal was also effectively ...[more]