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Nosocomial outbreak of carbapenem-resistant Pseudomonas aeruginosa with a new bla(IMP) allele, bla(IMP-7).

ABSTRACT: Pseudomonas aeruginosa isolates from an outbreak in Canada were highly resistant to carbapenems and ceftazidime but not piperacillin. They produced a novel integron-associated metallo-beta-lactamase, designated IMP-7, with 91% identity to IMP-1. bla(IMP-7) was not detected with standard bla(IMP)-specific primers, owing to mismatches in the forward primer.

SUBMITTER: Gibb AP

PROVIDER: S-EPMC126979 | biostudies-literature | 2002 Jan

REPOSITORIES: biostudies-literature

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Nosocomial outbreak of carbapenem-resistant Pseudomonas aeruginosa with a new bla(IMP) allele, bla(IMP-7).

Gibb Alan Patrick AP Tribuddharat Chanwit C Moore Richard A RA Louie Thomas J TJ Krulicki Wally W Livermore David M DM Palepou Marie-France I MF Woodford Neil N

Antimicrobial agents and chemotherapy 20020101 1

Pseudomonas aeruginosa isolates from an outbreak in Canada were highly resistant to carbapenems and ceftazidime but not piperacillin. They produced a novel integron-associated metallo-beta-lactamase, designated IMP-7, with 91% identity to IMP-1. bla(IMP-7) was not detected with standard bla(IMP)-specific primers, owing to mismatches in the forward primer. ...[more]

PMID: 11751148

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Project description: Not available

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