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Novel complex sul1-type integron in Escherichia coli carrying bla(CTX-M-9).

ABSTRACT: For the present report, a novel complex class 1 integron, In60, was characterized. Part of this integron includes the bla(CTX-M-9) gene and its downstream nucleotide sequence, which shares 81% and 78% nucleotide identity with those of kluA-1 beta-lactamase and orf3 of K. ascorbata, respectively. Furthermore, a new insertion sequence, IS3000, has been found in In60. PCR analysis indicates that integron In60 is present in 33 of 34 nonclonal enterobacterial isolates carrying the putative beta-lactamase CTX-M-9.

SUBMITTER: Sabate M

PROVIDER: S-EPMC127377 | biostudies-literature | 2002 Aug

REPOSITORIES: biostudies-literature

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Novel complex sul1-type integron in Escherichia coli carrying bla(CTX-M-9).

Sabaté Montserrat M Navarro Ferran F Miró Elisenda E Campoy Susana S Mirelis Beatriz B Barbé Jordi J Prats Guillem G

Antimicrobial agents and chemotherapy 20020801 8

For the present report, a novel complex class 1 integron, In60, was characterized. Part of this integron includes the bla(CTX-M-9) gene and its downstream nucleotide sequence, which shares 81% and 78% nucleotide identity with those of kluA-1 beta-lactamase and orf3 of K. ascorbata, respectively. Furthermore, a new insertion sequence, IS3000, has been found in In60. PCR analysis indicates that integron In60 is present in 33 of 34 nonclonal enterobacterial isolates carrying the putative beta-lacta ...[more]

PMID: 12121950

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