Ontology highlight
ABSTRACT:
SUBMITTER: Levinson DF
PROVIDER: S-EPMC1287525 | biostudies-literature | 2000 Sep
REPOSITORIES: biostudies-literature
Levinson D F DF Holmans P P Straub R E RE Owen M J MJ Wildenauer D B DB Gejman P V PV Pulver A E AE Laurent C C Kendler K S KS Walsh D D Norton N N Williams N M NM Schwab S G SG Lerer B B Mowry B J BJ Sanders A R AR Antonarakis S E SE Blouin J L JL DeLeuze J F JF Mallet J J
American journal of human genetics 20000802 3
Schizophrenia candidate regions 33-51 cM in length on chromosomes 5q, 6q, 10p, and 13q were investigated for genetic linkage with mapped markers with an average spacing of 5.64 cM. We studied 734 informative multiplex pedigrees (824 independent affected sibling pairs [ASPs], or 1,003 ASPs when all possible pairs are counted), which were collected in eight centers. Cases with diagnoses of schizophrenia or schizoaffective disorder (DSM-IIIR criteria) were considered affected (n=1,937). Data were a ...[more]