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Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003.


ABSTRACT: Avian H9N2 influenza A virus has caused repeated human infections in Asia since 1998. Here we report that an H9N2 influenza virus infected a 5-year-old child in Hong Kong in 2003. To identify the possible source of the infection, the human isolate and other H9N2 influenza viruses isolated from Hong Kong poultry markets from January to October 2003 were genetically and antigenically characterized. The findings of this study show that the human H9N2 influenza virus, A/Hong Kong/2108/03, is of purely avian origin and is closely related to some viruses circulating in poultry in the markets of Hong Kong. The continued presence of H9N2 influenza viruses in poultry markets in southern China increases the likelihood of avian-to-human interspecies transmission.

SUBMITTER: Butt KM 

PROVIDER: S-EPMC1287799 | biostudies-literature | 2005 Nov

REPOSITORIES: biostudies-literature

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Human infection with an avian H9N2 influenza A virus in Hong Kong in 2003.

Butt K M KM   Smith Gavin J D GJ   Chen Honglin H   Zhang L J LJ   Leung Y H Connie YH   Xu K M KM   Lim Wilina W   Webster Robert G RG   Yuen K Y KY   Peiris J S Malik JS   Guan Yi Y  

Journal of clinical microbiology 20051101 11


Avian H9N2 influenza A virus has caused repeated human infections in Asia since 1998. Here we report that an H9N2 influenza virus infected a 5-year-old child in Hong Kong in 2003. To identify the possible source of the infection, the human isolate and other H9N2 influenza viruses isolated from Hong Kong poultry markets from January to October 2003 were genetically and antigenically characterized. The findings of this study show that the human H9N2 influenza virus, A/Hong Kong/2108/03, is of pure  ...[more]

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