Ontology highlight
ABSTRACT:
SUBMITTER: Lee YA
PROVIDER: S-EPMC1287873 | biostudies-literature | 2000 Oct
REPOSITORIES: biostudies-literature
Lee Y A YA Rüschendorf F F Windemuth C C Schmitt-Egenolf M M Stadelmann A A Nürnberg G G Ständer M M Wienker T F TF Reis A A Traupe H H
American journal of human genetics 20000913 4
Psoriasis is a common chronic inflammatory skin disease with a strong genetic component. Few psoriasis-susceptibility loci have been reported, and only two have been confirmed in independent data sets. This article reports results of a genomewide scan that was performed, using 370 microsatellite markers, for psoriasis-susceptibility loci in 32 German extended families, comprising 162 affected and 195 unaffected individuals. Nonparametric linkage analysis of all families provided strong evidence ...[more]