Ontology highlight
ABSTRACT:
SUBMITTER: Auranen M
PROVIDER: S-EPMC378535 | biostudies-literature | 2002 Oct
REPOSITORIES: biostudies-literature
Auranen Mari M Vanhala Raija R Varilo Teppo T Ayers Kristin K Kempas Elli E Ylisaukko-Oja Tero T Sinsheimer Janet S JS Peltonen Leena L Järvelä Irma I
American journal of human genetics 20020821 4
To identify genetic loci for autism-spectrum disorders, we have performed a two-stage genomewide scan in 38 Finnish families. The detailed clinical examination of all family members revealed infantile autism, but also Asperger syndrome (AS) and developmental dysphasia, in the same set of families. The most significant evidence for linkage was found on chromosome 3q25-27, with a maximum two-point LOD score of 4.31 (Z(max )(dom)) for D3S3037, using infantile autism and AS as an affection status. S ...[more]