Ontology highlight
ABSTRACT:
SUBMITTER: Hirschhorn R
PROVIDER: S-EPMC129728 | biostudies-literature | 2002 Oct
REPOSITORIES: biostudies-literature
Hirschhorn R R Huie M L ML Kasper J S JS
Proceedings of the National Academy of Sciences of the United States of America 20021007 21
The exponential expansion of the publicly available human DNA sequence database has increasingly facilitated cloning by homology of genes for biochemically defined, functionally similar proteins. We hypothesized that an as-yet uncloned human alpha-glucosidase (human neutral alpha-glucosidase C or GANC) is a previously uncharacterized member of a paralogous human glycosyl hydrolase gene family 31, sharing sequence homology and related, but not identical, functions with other cloned human alpha-gl ...[more]