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Dual targeting of plastid division protein FtsZ to chloroplasts and the cytoplasm.

ABSTRACT: FtsZ is a filament-forming protein that assembles into a ring at the division site of prokaryotic cells. As FtsZ and tubulin share several biochemical and structural similarities, FtsZ is regarded as the ancestor of tubulin. Chloroplasts--the descendants of endosymbiotic bacteria within plant cells--also harbour FtsZ. In contrast to eubacteria, plants have several different FtsZ isoforms. So far, these isoforms have only been implicated with filamentous structures, rings and networks, inside chloroplasts. Here, we demonstrate that a novel FtsZ isoform in the moss Physcomitrella patens is located not only in chloroplasts but also in the cytoplasm, assembling into rings in both cell compartments. These findings comprise the first report on cytosolic localization of a eukaryotic FtsZ isoform, and indicate that this protein might connect cell and organelle division at least in moss.

SUBMITTER: Kiessling J

PROVIDER: S-EPMC1299139 | biostudies-literature | 2004 Sep

REPOSITORIES: biostudies-literature

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Dual targeting of plastid division protein FtsZ to chloroplasts and the cytoplasm.

Kiessling Justine J Martin Anja A Gremillon Louis L Rensing Stefan A SA Nick Peter P Sarnighausen Eric E Decker Eva L EL Reski Ralf R

EMBO reports 20040901 9

FtsZ is a filament-forming protein that assembles into a ring at the division site of prokaryotic cells. As FtsZ and tubulin share several biochemical and structural similarities, FtsZ is regarded as the ancestor of tubulin. Chloroplasts--the descendants of endosymbiotic bacteria within plant cells--also harbour FtsZ. In contrast to eubacteria, plants have several different FtsZ isoforms. So far, these isoforms have only been implicated with filamentous structures, rings and networks, inside chl ...[more]

PMID: 15319781

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