Ontology highlight
ABSTRACT:
SUBMITTER: Spigaglia P
PROVIDER: S-EPMC130716 | biostudies-literature | 2002 Sep
REPOSITORIES: biostudies-literature
Spigaglia Patrizia P Mastrantonio Paola P
Journal of clinical microbiology 20020901 9
The pathogenicity locus (PaLoc) of Clostridium difficile contains toxin A and B genes and three accessory genes, including tcdD and tcdC, which are supposed to code for the positive and negative regulators of toxin expression, respectively. Different studies have described variations in C. difficile toxin A and B genes, but little is known about C. difficile variants for the accessory genes. The PaLoc of several C. difficile clinical isolates was investigated by three different PCR methods with ...[more]